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95% CI 0.86, 0.93 at 7 years) for both liraglutide and semaglutide among GLP-1RAs.69 This study was included in another analysis including both randomised and some of the non-randomised data previously presented and reported a lower risk of all-cause dementia associated with any GLP-1RA.70 Two further network meta-analyses of selected publications71 72 ranked GLP-1RAs second for reducing the risk of dementia, including AD

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Science (2021)

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13 The absence of Tyr 1 from the N-terminal of GIP dramatically decreases its activity

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Amoscato AA, Anthonymuthu T, Kapralov O, Sparvero LJ, Shrivastava IH, Mikulska-Ruminska K

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