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(PubMed) Tiemeier H, van Tuijl HR, Hofman A, Meijer J, Kiliaan AJ, Breteler MM

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Dysregulation in energy metabolism is intricately associated with the pathogenesis of various disorders, encompassing neurological diseases, cardiovascular conditions, metabolic syndromes, autoimmune disorders, and cancer

The contents of other metabolites in feces were all lower than 0.06% of the administered amount, and it was impossible to perform structural identification because of the extremely low content

Furthermore, the authors reported that the MCF-7 breast cancer cell line shows an E2-dependent increase in its survival rate, which is abrogated by pre-treating them with the anti-estrogenic compounds ICI-182, 780, or raloxifene (Yu et al., 2012)