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Particular attention is given to suppression of the hypothalamicpituitarygonadal axis, impaired spermatogenesis, fertility disturbances, and the potential for long-term or persistent endocrine sequelae

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is projected to rise at 5.2% CAGR through 2036

doi: 10.1016/j.syapm.2021.126251 53 ChochuaS.DAcremontV.HankeC.AlfaD.ShakJ.KilowokoM.et al