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Informed by recent studies from 2024-2025, future research should prioritize the development of disease-specific ferroptosis biomarkers, optimization of combination therapy regimens, creation of next-generation modulators with enhanced cell-type specificity and pharmacokinetic properties, and elucidation of ferroptosis crosstalk with other regulated cell death pathways (152)

PMID 34665524

Chemotherapy 63, 293300

N Engl J Med 290:13991402 Krauskopf J, Caiment F, Claessen SM, Johnson KJ, Warner RL, Schomaker SJ, Burt DA, Aubrecht J, Kleinjans JC (2015) Application of high-throughput sequencing to circulating microRNAs reveals novel biomarkers for drug-induced liver injury

5) Antioxidant support for daily environmental stress Skin deals with oxidative stress constantlyUV exposure, pollution, and general environmental wear-and-tear