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Krzyak, D

Tirzepatide induced significant weight loss and a notable reduction in the composite endpoint of death and worsening heart failure events in patients with obesity-related HFpEF

It may also support those who need to treat diabetes , under proper medical supervision

If you take tirzepatide alongside other glucose-lowering medications, taking your dose early creates a period of enhanced glucose reduction that can tip you into hypoglycemia

In the STEP 1 trial, about 10% of participants achieved less than 5% weight loss, roughly the same as placebo response

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