this phenomenon has been linked with the increased resistance at doxorubicin treatment due to the lack of CT2 in the cell membrane that, in turn, impairs drug entry into cancer cells (Novak et al., 2015)
J Biol Chem 256:1238712392 Larraufie M-H, Yang WS, Jiang E et al (2015) Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility
Biochem Pharmacol 33:32353239
Comparison of the interaction of doxorubicin, daunorubicin, Idarubicin and Idarubicinol with large unilamellar vesicles
The fat-adapted advantage after stopping People who have spent several months in ketosis develop metabolic flexibility that persists after they transition off strict keto
Why Body Composition Matters More Than Scale Weight This brings us to why growth hormone pathway peptides matter profoundly for body recomposition