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Although the exact mechanisms by which GLP-1 RAs mitigate ischemic injury are not fully understood, the pleiotropic mechanisms seem to extend beyond glycemic regulation, with beneficial effects observed in nondiabetic animal models
They significantly inhibit apoptosis, anti-inflammatory responses, protect synaptic function, promote the release of neurotrophic factors, and outperform GLP-1 single receptor agonists
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(2000) 13(5 Pt 2):62S7S
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