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While the clinical relevance of these findings in a population largely free from kidney disease remains uncertain, the reductions in albuminuria, blood pressure, and the favourable safety profile support further investigation of retatrutides potential kidney-protective effects in high-risk populations

At the same time, it encourages your pancreas to release insulin after you eat and reduce its glucagon production

Patient stratification probably matters more than any single drug choice, because the variable results likely conceal responder subgroups

Symptoms of GLP-1 induced gastroparesis often match other common GI disorders

Gitanjali Srivastava, MD, is co-director of Vanderbilt Weight Loss Clinics

Elevated liver enzymes in long-term use