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Their primary mechanisms of action include: Stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner Suppressing glucagon release , which reduces glucose production by the liver Slowing gastric emptying , which helps control post-meal blood sugar rises Reducing appetite through effects on brain centres that regulate hunger In the UK, GLP-1 receptor agonists are licensed for the treatment of type 2 diabetes mellitus and, in some cases, for weight management in adults with obesity or overweight with weight-related comorbidities

Because the FDA does not review supplements for efficacy before they hit the market, the burden of quality falls on the brand

For these individuals, baseline calcitonin and thyroid ultrasound before starting tirzepatide, with periodic follow-up, is prudent

Note : You can check out my full review of menopause-friendly GLP-1 brands here

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