Nat Metab 4: 389403
While the above evidence indicates that the mitochondrial apoptotic pathway promotes cell death, recent provocative evidence has shown that the intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in Caenorhabditis elegans by triggering a unique pattern of gene expression that modulates stress sensitivity and promotes survival (Yee et al., 2014)
Shi Y, Ma C, Peng L, Yu G (2015) Conductive smart hybrid hydrogels with PNIPAM and nanostructured conductive polymers
Unexplained infertility may be due to increased oxidative stress load and a depleted antioxidant reservoir to combat the toxic effects of oxidative stress
Thus, the therapeutic use of iron modulation must be context-dependent, guided by tumour stage, subtype, and metabolic profile
Invest Ophthalmol Vis Sci 58:22752283