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Obviously, they occurred before the initiation of angiogenesis (Sikiric et al., 1993
Deficiency In healthy adults, overt vitamin B 12 deficiency is uncommon, mainly because total body stores can exceed 2,500 g, daily turnover is slow, and dietary intake of only 2.4 g/day is sufficient to maintain adequate vitamin B 12 status (see The RDA) (4)
For individuals with severe B12 deficiency (especially those with anaemia or neurological symptoms), some might start to feel an improvement in their energy levels within a few days to a week
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