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The traditional classification of DM is mainly based on abnormalities in insulin secretion and action, such as type 1 DM due to an absolute lack of insulin secretion and T2DM due to insulin resistance and relative insulin deficiency
Constipation is reported less frequently than nausea or diarrhoea in clinical trials, nevertheless it remains a significant and sometimes persistent concern in real-world use
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Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ, Yancopoulos GD
The toxicology of hydroquinone - relevance to occupational and environmental exposure