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A randomized, placebo-controlled trial in 559 elderly individuals with low serum levels of folate and vitamin B 12 and at increased risk of fracture evaluated the combined supplementation of very high doses of folic acid (5 mg/day) and vitamin B 12 (1.5 mg/day)
The discomfort is typically minimal and brief
Pale or jaundiced skin , often linked to megaloblastic anemia from inadequate B12
Acceptable alternative options have only recently become available
Energy and Metabolism Enhancement One big advantage of B12 injections is boosting energy and metabolism
Temperature excursions above 8C cause irreversible structural changes to the peptide backbone, rendering it inactive even if it appears visually unchanged
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