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Gries M, Christmann A, Schulte S, Weyland M, Rommel S, Martin M, et al
Figure 1 Figure 2 The discovery of the second incretin, GLP-1, originated from observations in 1982 that anglerfish proglucagon mRNA contained coding sequences of glucagon-related peptide, flanked by pairs of basic amino acids characteristic of the sites cleaved during post-translational processing of prohormones ( Figure 1 Section A]
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Source: Xie et al., Signal Transduction and Targeted Therapy (2020)
In cases of serious adverse effects such as acute pancreatitis or severe allergic reactions, discontinuation is warranted with appropriate specialist referral
Although iodine deficiency was associated with goitre and thyroid nodules, PTC appears to be more common in areas with high iodine intake, which points to the complex relationship between iodine intake and thyroid disease (174)
