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It is protecting lean mass, stabilizing hormones, and feeling well while doing it
In a trial of semaglutide, people who switched to a placebo regained around 7% of their body weight over the following year, while those who kept taking the medication lost a further 8%
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Other activators of pancreatic beta cells Incretin hormone receptor agonists (discussed below) can reduce beta cell apoptosis in vitro and in animal models, probably via cAMP and protein kinase A (PKA) activation, and provide the best evidence-supported opportunity to preserve the beta cell population at this time
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