This most commonly occurs when bacteriostatic water was contaminated during draw, when the vial was shaken instead of gently swirled during mixing, or when the peptide was exposed to temperatures above 25C before reconstitution
51 As GSH is known to be present in CSF at very low concentrations (~0.2 mol/l in both healthy and PD subjects), 52 relative to brain tissue concentrations (~1 mmol/l), 7 LCModel-calculated Cr concentrations ( C measured ) were corrected ( C corrected ) using the following formula, which assumes negligible contribution of CSF GSH to the total GSH signal: Absolute GSH levels (IU) were calculated by multiplying GSH/Cr ratios by CSF-corrected absolute Cr concentrations (IU)
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Cureus 15 (8), e43697