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The melanotic macules are usually brown, deep blue/black, or black, and they are well circumscribed with sharp, delineated borders

10.1177/03635465990270031701 42 LaiF.WangJ.TangH.HuangP.LiuJ.HeG.et al (2022)

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doi:10.1007/s11064-011-0413-6 Masahiko I, Kazumasa M, Schoichiro T (1999) Characterization of ZO-2 as a MAGUK family member associated with tight as well as adherens junctions with a binding affinity to occludin and a catenin

The study "Liraglutide versus placebo as an adjunct to glucose-lowering therapy in patients with type 2 diabetes and moderate renal failure" (LIRA-RENAL) did not demonstrate a benefit of liraglutide in lowering eGFR, although the duration of the study (26 weeks) may have been insufficient to show an effect