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Often called the master antioxidant, glutathione supports cellular repair, neutralizes free radicals, and helps brighten the skin over time

Bcl-2 and OGC appear to act in a coordinated manner to increase the mGSH pool and to enhance the resistance of neurons to mitochondrial oxidative stress

Food and Drug Administration (FDA) for safety or efficacy

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Conclusion Although topical glutathione shows promise for dermatological applications, further larger randomized controlled trials with long-term follow-up are necessary to evaluate its utility more comprehensively in improving hyperpigmentation, erythema, and reducing free-radical damage