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In living cells, when fat metabolism produces energy, carnitine is required to transport fatty acids from the cytosol to the mitochondria to prevent fatty acids from accumulating in the cells
Upadacitinib induction and maintenance therapy improves abdominal pain, bowel urgency, and fatigue in patients with ulcerative colitis: a post hoc analysis of phase 3 Data
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In addition, reduction of inflammatory factors, reduction of angiotensin II, and improvement of blood sugar and blood pressure by GLP-1RAs have been suggested as mechanisms of kidney protection effect
Prolonged treatment with N-acetylcysteine and L-arginine restores gonadal function in patients with polycystic ovary syndrome
Consequently, inhibition of GSH synthesis, impairment of GPX4 function, or certain pathophysiological conditions can all trigger ferroptosis
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