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Intravenous delivery results in immediate full-concentration exposure and typically the shortest apparent half-life because peak plasma levels degrade the fastest

As a result, many researchers and clinicians now advocate for more cautious, limited use during pregnancy

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Specifically, these studies show a reduction in the diversity of gut microbiota in patients with depression, along with altered abundances of specific bacterial communities

Although the DSM-IV [44] does not explicitly define residual schizophrenia, it describes as typical a course of the illness in which positive symptoms diminish while negative symptoms persist

Neuron 71 , 656670 (2011)