Before Wegovy is approved for coverage in a female who can become pregnant, the healthcare provider will confirm a negative pregnancy test and counsel the patient on using effective birth control and potential risks of becoming pregnant during treatment
These proteases exist as inactive zymogens and require proteolytic cleavage to become enzymatically active
Geroscience 47 (3), 44134427
Mller TD, Finan B, Bloom SR, DAlessio D, Drucker DJ, et al
Zmitek K, Amitek J, Hristov H, Butina MR, Kersmanc P, Pogacnik T
Over the next decade, several longer-acting versions were developed, including: Victoza (liraglutide) approved in 2010 Bydureon approved in 2012 Trulicity approved in 2014 During this period the medications were primarily prescribed for diabetes , and awareness outside medical circles was relatively limited