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One rest days take with a carbohydrate rich meal

They slow gastric emptying, alter gut motility, and shift the bacterial landscape of your intestines

These disorders can lead to the build-up of harmful metabolites in the body, such as methyl malonic aciduria, propionic acidemia, glutaric aciduria, and medium chain fatty acetyl dehydrogenase deficiency

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This study documents a positive association between frequency of MTHFR -C677T and MTHFR -A1298C polymorphisms and latitude, with increases in latitude significantly associated with increased frequency of the polymorphic allele of these variants