J Clin Endocrinol Metabol 86:15041510 Ben-Amitai D, Laron Z (2009) Insulin-like growth factor-1 (IGF-1) deficiency prevents the appearance of pre-acne and acne (Abstract PO2-186) 8th Joint Meeting of the LWPES/ESPE, New York, 912 Sep 2009
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But the full effects usually take a bit longer to show up