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Moreover, this study also raises awareness of gastrointestinal adverse events induced by GLP-1RAs, and concerns about safety are especially warranted for high dose administration

Burukoglu D, Baycu C

[10] The loss of essential dietary elements such as zinc, magnesium, and iron is common, especially with prolonged therapy, potentially leading to fatigue, weakened immunity, or neurological disturbances

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But the SEMALEAN data suggests that semaglutide does not inherently destroy muscle in the way some early headlines suggested, especially when patients maintain adequate protein and physical activity

Hippocampus 24 , 257269 (2014)