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The Congressional Budget Office estimates that expected costs range from less than $1 billion to more than $2 billion when including capital costs and expenditures on drugs that ultimately fail to reach the market

This includes not rotating injection sites, which can cause skin irritation, redness, and swellingsome of the most common side effects

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Room temperature exposure may be acceptable during transport or shipping

Folate and vitamin B12 supplements may help lower homocysteine levels in the blood while increasing energy and overall well-being