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Key Contraindications (Both) Active malignancy or recent cancer history, pregnancy, breastfeeding, uncontrolled diabetes, severe pituitary disease

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Retatrutide Dosage Considerations in Special Research Populations The Phase 2 trial enrolled a relatively homogeneous population of adults with obesity or overweight and at least one comorbidity, with a mean baseline BMI of approximately 37 kg/m

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Compared to the control group, the fibrin clot containing IGF-1 (25 g/mL) for fracture repair inhibited chondrocyte apoptosis in vivo [33]