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Review FRAT testing Screen the Pattern, Then Confirm Undermethylation and Mitochondrial Stress With Testing Symptoms can suggest possible undermethylation or mitochondrial stress, but laboratory findings help distinguish low SAM, elevated SAH, oxidative damage, copper-zinc imbalance, pyroluria and functional nutrient needs

However, emerging evidence requires this idea to be reconsidered

These supplements may provide systemic benefits, supporting overall skin health, hair growth, and internal tissue repair

Circulation 98: 1724

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