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Aucubin, a naturally occurring iridoid glycoside inhibits TNF--induced inflammatory responses through suppression of NF-B activation in 3T3-L1 adipocytes

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The molecular basis appears to be the slightly different binding pose at GHSR-1a that avoids sufficient activation of the signaling branches coupling to ACTH release

10.1016/j.neurobiolaging.2019.08.006 Neurobiol