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BPC-157 works primarily at the injury site for local tissue repair, while TB-500 has more systemic effects on muscle repair, inflammation, and flexibility

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Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy

NSAIDs also have harmful effects on the liver, kidneys, GI tract and cardiovascular system, while steroids can affect blood sugar levels and cause weight gain, exacerbating metabolic issues that contribute to knee OA

With this in mind, we will break down the structure, mechanisms, and activity of each of the peptides and discuss their synergistic potential, which should be investigated in future laboratory experiments