Combining NAD+ and glutathione may support energy production, detox pathways, and metabolic health
doi: 10.1016/S0140-6736(21)01751-7
It is not typically a sign of a severe medical condition
Gastrectomy for any reason (eg, gastric cancer, bariatric surgery) increases the risk of deficiency because parietal cells, the source of intrinsic factor, are removed (17
The reason is simple: those guides are written by people who've read other guides, not by researchers who've troubleshot failed protocols and traced the failure back to the reconstitution step
Some people swear by BCAA supplements, though the research on their benefits is inconclusive and sometimes conflicting