Baumgardner JN, Shankar K, Hennings L, et al
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It is slightly more prone to foaming if agitated vigorously
Some researchers tolerate dose increases faster
Keep vials clean during preparation to reduce contamination risks
550 In Phase II trials (KARDIA-1), zilebesiran reduced systolic blood pressure in all treated patients, with effects lasting 6 months, opening new possibilities for NADs use in treating hypertension and CVDs