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Oral administration of these conjugates significantly improved glucose-lowering effects compared to native GLP-1, with DBP-GLP-1 showing superior efficacy likely attributed to enhanced intestinal absorption

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This makes it a triple agonist , interacting with the following receptors to promote fat burning, blood sugar control, and appetite reduction: GLP-1 (Glucagon-like peptide-1) GIP (Glucose-dependent insulinotropic polypeptide) GCG (Glucagon) Weekly Injection with Long-Lasting Effects Administered as a weekly injection, Retatrutide stays active in the body for approximately six days

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doi: 10.3390/nu14214549

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