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Low levels of B12 have been linked to a higher risk of dementia and Alzheimers disease

Science 308 , 14661469 (2005)

A., Mooney, D

Contraindications and Precautions Consider avoiding BPC-157 if you have: History of cancer or active malignancy Pregnancy or breastfeeding (no safety data) Competitive athletic status (WADA prohibits peptides) Known sensitivity to peptide products Severe cardiovascular disease (limited data) Blood pressure monitoring may be prudent given the nitric oxide modulation effects

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In addition to the above, isorhapontigenin mitigates diabetic cardiac microvascular injury by inhibiting mitochondria-associated ferroptosis via the PRDX2/MFN2/ACSL4 pathway [111]