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Tubular function GH-deficient children and adults display reduced sodium and total body water content and reduced extracellular and plasma volume compared to healthy subjects, while body fat mass is increased [137, 138]

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Meanwhile, vitamin C itself scavenges ROS in aqueous environments, particularly in the cytoplasm and extracellular fluids

PMID: 31539514

High-sensitivity MRM measurements were then used for targeted analysis of modified peptides, using reference standards of all possible cysteine modified peptides

Acts as a potent endogenous antioxidant, regulating pro- and anti-inflammatory pathways, and protecting against DNA damage and lipid peroxidation