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The nuclear protein fraction was extracted, and the relative Dnmt and 5-mC hydroxylase Tet activities were calculated based on the ratio of the treatment group to the control group after the normalization to the amount of protein

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Whether supplementing with exogenous antioxidants like glutathione reverses this deficit in a clinically meaningful way remains unproven

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22 Vitamin C, or ascorbic acid, is a water-soluble vitamin found in a variety of foods, particularly fruits and vegetables

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Miranda-Daz et al

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PMX500FI, a synthetic carnitine-conjugated -lipoic acid derivative, can cross the bloodretinal barrier and improve mitochondrial function [321]

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The strategy of covalently conjugating metal-based anticancer agents to amphiphilic polymers, that could self-assemble into nanoparticles, could present a method for the tumor-selective anticancer therapy

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