The nuclear protein fraction was extracted, and the relative Dnmt and 5-mC hydroxylase Tet activities were calculated based on the ratio of the treatment group to the control group after the normalization to the amount of protein
Whether supplementing with exogenous antioxidants like glutathione reverses this deficit in a clinically meaningful way remains unproven
22 Vitamin C, or ascorbic acid, is a water-soluble vitamin found in a variety of foods, particularly fruits and vegetables
Miranda-Daz et al
PMX500FI, a synthetic carnitine-conjugated -lipoic acid derivative, can cross the bloodretinal barrier and improve mitochondrial function [321]
The strategy of covalently conjugating metal-based anticancer agents to amphiphilic polymers, that could self-assemble into nanoparticles, could present a method for the tumor-selective anticancer therapy