[6] After parenteral delivery, cyanocobalamin binds transcobalamin II, permitting receptor mediated endocytosis into virtually all nucleated cells
Your team may advise a temporary pause based on current guidance
Reference Tuell JL, Bhattacharya D, Leeuwenburgh C, Chaudhuri A, Kumar V
USP7 deubiquitinates DNA methyltransferase (DNMT1), resulting in increased stability of DNMT1
Inaishi J, Saisho Y (2022) Exenatide once weekly for management of type 2 diabetes: a review
It is interesting to note that the positive effect of tirzepatide on body weight is associated with a significant improvement in quality of life and physical performance [50] and is independent of sex [51], baseline body mass index (BMI) [52] and potential side effects, predominantly gastrointestinal [53]