Revised 09/2021
Ubiquitin ligase E3 HUWE1/MULE targets transferrin receptor for degradation and suppresses ferroptosis in acute liver injury
It can promote tissue repair, reduces inflammation, enhances angiogenesis (new blood vessel formation), and remains stable in gastric juice enabling effective oral administration
(PubMed) Glynn RJ, Ridker PM, Goldhaber SZ, Zee RY, Buring JE
An imbalance between SOD activity and GPX was proposed as an important determinant of molecular ageing, since the resultant hydroxyl radicals which are highly reactive could cause damage to macromolecules such as DNA, protein and lipids (Bar-Peled, Korkotian, Segal & Groner, 1996
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