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Because these were controlled studies, the poor responders weren't simply skipping doses

Untreated, sleep apnea can lead to high blood pressure, heart disease, stroke, and diabetes

Individual side effect profiles vary considerably

The data conclusively demonstrated that both ME/CFS and Long COVID are characterized by severe, elevated oxidative stress and profound mitochondrial damage, forcing immune cells to consume excess host energy

doi: 10.1016/j.bbrc.2009.10.054 41 Portela-GomesGMHoogA

Mitochondrial Function Studies: Analysis of oxidative phosphorylation, respiratory chain function, ATP production, and mitochondrial membrane potential