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In mouse models of NASH, GLP-/GIP dual agonists have also been found to significantly reduce TG and LDL-C and increase high-density lipoprotein cholesterol (HDL-C) [127]

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Kumar P, Liu C, Suliburk J, et al

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Second, the rules shifted recently: after the FDA declared the semaglutide shortage resolved in early 2025, the special allowances that let pharmacies widely compound semaglutide were phased out over that year