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If you have established osteoporosis, ensure appropriate treatment (bisphosphonates, denosumab, or other bone-specific therapies) is optimized before and during tirzepatide therapy

For someone with Hashimotos or hypothyroidism, adding these side effects on top of things like fatigue and hair loss can be completely debilitating

Patients should be clearly informed of the signs that distinguish manageable side effects from potentially serious complications

That the FDA/EMA approval of afamelanotide extends to cosmetic tanning, or to Melanotan 2 in any form it does not

The chronic unpredictable stress model was also associated with similar neurobehavioural changes[55]