Additionally, the FDA has reported over 455 adverse events with compounded Semaglutide as of February 28, 2025, raising safety concerns (FDAs Concerns with Unapproved GLP-1 Drugs)
Compounded tirzepatide contains the same active molecule and acts through the same mechanism
Common Side Effects Low blood sugar (hypoglycemia) : Shakiness, sweating, dizziness, rapid heartbeat, or confusion when blood sugar drops too quickly
First, it acts as an antioxidant, neutralising free radicals that damage cells, including the cells in hormone-producing glands like the ovaries, adrenals, and thyroid
See the tirzepatide constipation treatment guide and the tirzepatide diarrhea guide for management strategies
The 0.25 mg starting dose is primarily about tolerability, not therapeutic effect