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A 2021 review found modest fat-loss support when combined with diet and exercise, but results are inconsistent and rarely exceed diet-only controls
People on a GLP-1 are sharing their experience on Reddit, saying that after years as a daily biter, they stopped entirely once they started injecting themselves with the semaglutide medication
If anything, stopping and restarting introduces additional variability and side effect periods without improving outcomes
What the evidence does show: a sustained national decline in adult obesity over four years, running concurrently with a dramatic increase in GLP-1 prescriptions a pattern that public health researchers say is consistent with the drugs' documented clinical efficacy
Addressing withdrawal symptoms medically prioritizes safety and gives patients the extra help of addiction medication treatments
Our study is observational and these results should therefore be replicated in a randomised controlled trial to confirm and extend our findings, said Dr Max Taquet, Clinical Lecturer at the University of Oxford and senior author of the study
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