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Potential Thyroid Concerns: GLP-1s carry a warning for potential risk of medullary thyroid carcinoma (MTC) in animal studies, though this has NOT been confirmed in humans
J Neurochem (2003) 87(5):113744
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In summary, moderately promoting oxidative stress has potential application value in the treatment of certain diseases
Funding The present study was supported by the National Natural Science Foundation of China (82422003), Huazhong University of Science and Technology Fundamental Research Program, the Tongji Hospital (HUST) Foundation for Excellent Young Scientists and, Hubei Provincial Medical Youth Elite Talent Program (SCZ202412), the Tongji Hospital (HUST) Cultivation Program (2024B35)
Mechanism-based inhibition of iPLA2 demonstrates a highly reactive cysteine residue (C651) that interacts with the active site: mass spectrometric elucidation of the mechanisms underlying inhibition
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