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Prepare for some residual laxity or visible scarring
This creates positive pressure inside the vial, making it much easier to draw water out
Pratley, R., et al., Oral semaglutide versus subcutaneous liraglutide and placebo in type 2 diabetes (PIONEER 4): a randomised, double-blind, phase 3a trial
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The moment you introduce a liquidthe process of reconstitutionyou 'wake it up.' You're returning it to its biologically active state, but you're also starting a ticking clock on its stability
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