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These alterations in brain structure may facilitate the entry of toxic substances and peripheral inflammatory mediators into the brain, thereby triggering neuroinflammation

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Conclusions and Future Perspectives Overall, GLP-1RAs are considered novel blood glucose lowering drugs used in the treatment of T2MD (229), owing to their advantages of lowering blood pressure, lowering the levels of fasting blood glucose, lowering HbA1c, inducing weight loss, and being associated with a low incidence of hypoglycemia

Adjustment: After 14 days, the dose was titrated according to the manufacturers guidelines (FDA label) to bring blood testosterone into the normal male range (up to a max of 81 mg/day)

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