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Age-related brain cerebrovascular and brain parenchymal changes observed were also accompanied by changes in the periphery, with E2 mice retaining profiles similar to that of younger mice of other genotypes even as they age

This is just an observational study so there can be no conclusions about the medications being the definitive cause of the decreased risk of Alzheimers and/or dementia. Jennifer Cheng, DO For research next steps, it would be interesting to see the new GLP-1 medications, and effects of the GLP-1s, studied to see if it is definitive, Cheng added