Ngetich E, Lapolla P, Chandrashekar A, Handa A, Lee R (2022) The role of dipeptidyl peptidase-IV in abdominal aortic aneurysm pathogenesis: a systematic review
and PT-141, marketed for low libido
Ongoing research continues to expand our understanding of these medications long-term effects and optimal usage
Semaglutide and tirzepatide are the two FDA-approved medications in this class, and both have a substantial base of randomized trial evidence behind them, including weight reductions in the range of 1522% of body weight over roughly a year and a half in trial populations (NEJM)
Many patients begin their journey with medications and later move on to surgery when they need more permanent results
Users who have been on semaglutide long-term or those considering maintaining results after tirzepatide should view dry mouth management as an evolving practice rather than a one-time fix