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Even in settings where clinical response to biologics is preserved, the presence of obesity provides a strong rationale for adjunctive metabolic interventions
Research shows that methylated B12 may reduce inflammation by mitigating homocysteine (3)
Quinine iris toxicity
The extended half-life of approximately 5 days allows for convenient weekly dosing, improving adherence compared to daily injectable therapies
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The primary outcome was the first occurrence of a composite endpoint of non-fatal myocardial infarction, non-fatal stroke, or cardiovascular death
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