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Congenital transcobalamin II deficiency may cause megaloblastic anemia and neurologic abnormalities despite normal serum cobalamin levels (105)

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Visual Format: Approved vs investigational status map Key Labels: Cosmetic product, compounded peptide, non-injectable route, injectable route, FDA safety concern, approved drug label, regulatory standards, product category Suggested Layout: Use a horizontal status map with four blocks: Cosmetic context, Non-injectable compounding review, Injectable safety concern, and Approved drug labeling. Add a note that product category changes evidence and safety interpretation

High vitamin B12 levels are often seen as less concerning because they usually dont cause symptoms and are typically the sign of an underlying condition, not a direct health risk 2 , 5

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Yoon, H