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Target engagement remains context dependent, and metabolic mediation would require direct testing in adipocytes, adipose tissue, and whole-body metabolic models

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Richardson, A., & Park, W

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This is often just the body adjusting to a new supplement and typically resolves within a few days

Cysteine can be metabolized into cysteine sulphinate (via CDO1), which then can produce hypotaurine (via CSAD) 40